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Vincristine domide-Propargyne-PEG3-COOH (2013) J Med Chem

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Description

(2013) J Med Chem

3-((6-(Benzylamino)-9-isopropyl-9H-purin-2-yl)amino)propan-1-ol

Yoshimura A

MLN-9708 dramatically increases the number of cleaved-caspase-3 positive cells of the xenograft mode

InChi: InChI=1S/C154H244N48O29/c1-18-87(11)121-141(226)190-108(73-84(5)6)131(216)188-112(78-118(206)207)136(221)199-153(16

Vincristine domide-Propargyne-PEG3-COOH (2013) J Med ChemVincristine (Leurocristine, NSC 67574, 22 Oxovincaleukoblastine) is a natural alkaloid isolated from the plant Vinca rosea Linn. with anti tumor activity. Vincristine inhibits microtubule formation in mitotic spindle and binds to microtubule with Ki of 85 nM. Product information CAS Number: 57 22 7 Molecular Weight: 824. 96 Formula: C46H56N4O10 Chemical Name: methyl 11 (acetyloxy) 12 ethyl 4 [17 ethyl 17 hydroxy 13 (methoxycarbonyl) 1,11

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